A.A. 2022/2023

A.A. 2021/2022

A.A. 2020/2021

A.A. 2019/2020

A.A. 2018/2019

1. Pubblicazione First Examples of b-Diketonate Platinum(II) Complexes with Sulfoxide Ligands. Eur. J. Inorg. Chem. 2005, 788–796;
2. Pubblicazione New Water-soluble platinum(II) phenanthroline complexes tested as cisplatin analogues: first-time comparison of cytotoxic activity between analogous four- and five-coordinate species. Dalton Trans., 2006, 5077–5087;
3. Pubblicazione New platinum(II) complexes containing both an O,O'-chelated acetylacetonate ligand and a sulfur ligand in the platinum coordination sphere induce apoptosis in HeLa cervical carcinoma cells. Biochemical Pharmacology, 2007, 74, 28-40;
4. Pubblicazione Highly selective metal mediated ortho-alkylation of phenol. First platinum containing organometallic chromane analogues. Dalton Trans., 2007, 5720–5725;
5. Pubblicazione [Pt(O,O’-acac)(γ-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway. British Journal of Pharmacology, 2008, 153, 34–49;
6. Pubblicazione New mononuclear and homodinuclear Pt(II) complexes with heterocyclic nitrogen chelates: Synthesis, characterization, intercalating ability and in vitro cytotoxic activity evaluation. Dalton Trans., 2008, 5911–5921;
7. Pubblicazione Hard/soft selectivity in ligand substitution reactions of b-diketonate platinum(II) complexes. Dalton Trans., 2009, 7786–7795;
8. Pubblicazione Comparison among Different Gilthead Sea Bream (Sparus aurata) Farming Systems: Activity of Intestinal and Hepatic Enzymes and 13C-NMR Analysis of Lipids. Nutrients, 2009, 1, 291-301;
9. Pubblicazione Sublethal concentrations of the platinum(II) complex [Pt(O,O’-acac)(g-acac)(DMS)] alter the motility and induce anoikis in MCF-7 cells. British Journal of Pharmacology, 2010, 160, 1362–1377;
10. Pubblicazione Investigating potential effects of RFID systems on the molecular structure of the human insulin, 2010, CIBEC 2010, pp. 192-196;
11. Pubblicazione Potential effects of RFID systems on biotechnology insulin preparation: A study using HPLC and NMR spectroscopy, 2010, CME2010, pp 198-203;
12. Pubblicazione Mutagenic Tests ConfirmThat New Acetylacetonate Pt(II) Complexes Induce Apoptosis in Cancer Cells Interacting with Nongenomic Biological Targets. Metal-Based Drugs, Volume 2011, 1-10;
13. Pubblicazione Developing Central Nervous System and Vulnerability to Platinum Compounds. Chemotherapy Research and Practice, Volume 2011, 1-14;
14. Pubblicazione The platinum (II) complex [Pt(O,O’-acac)(g-acac)(DMS)] alters the intracellular calcium homeostasis in MCF-7 breast cancer cells. Biochemical Pharmacology, 2011, 81, 91-103;
15. Pubblicazione The signalling axis mediating neuronal apoptosis in response to [Pt(O,O’-acac)(gamma-acac)(DMS)]. Biochemical Pharmacology, 2011, 81, 1271-1285;
16. Pubblicazione The developmental neurotoxicity study of platinum compounds. Effects of cisplatin versus a novel Pt(II) complex on rat cerebellum. Neurotoxicology and Teratology, 2011, 33, 273–281;
17. Pubblicazione The lipidic extract of the seaweed Gracilariopsis longissima (Rhodophyta, Gracilariales): a potential resource for biotechnological purposes?. New Biotechnology, 2012, 29(3), 443-450;
18. Pubblicazione Pentacoordinate [PtCl2(h2-C2H4)(N-N’)] complexes with asymmetrically hindered nitrogen donor chelates. Stereospecific synthesis of syn- and anti-[PtCl(h1-CH2CH2OMe)(Mebpy)]. Journal of Organometallic Chemistry, 2012, 714, 60-66;
19. Pubblicazione Alkyl-vinyl-ethers from alcoholic substrates and the Zeise’s salt, via square planar [PtCl(N-N)(h1-CH2CH2OR)] complexes. Journal of Organometallic Chemistry, 2012, 714, 104-108;
20. Pubblicazione Developmental expression of cellular prion protein and apoptotic molecules in the rat cerebellum: Effects of platinum compounds. Journal of Chemical Neuroanatomy, 2012, 46, 19–29.
21. Pubblicazione Cisplatin-related drugs for nongenomic targets: Forcing the reactivity with nucleobases. Pure Appl. Chem., 2013, 85(2), 355–364;
22. Pubblicazione A new platinum (II) compound anticancer drug candidate with selective cytotoxicity for breast cancer cells. Cell death & disease, 2013, 4, e796.
23. Pubblicazione Platinum drugs and neurotoxicity: effects on intracellular calcium homeostasis. Cell biology and toxicology, 2013, 29(5), 339-353.
24. Pubblicazione NMR-metabolomic study on monocultivar and blend salento EVOOs including some from secular olive trees, Foods and Nutrition Sciences, 2014, 5(1), 89-95.
25. Pubblicazione Synthesis, characterization and cytotoxicity of novel Pt (II) κ2O, O′-acetylacetonate complexes with nitrogen ligands, Inorganica Chimica Acta, 2014, 412, 88-93.
26. Pubblicazione Synthesis, Crystal Structure, and Biological Study of PtII Complexes with 4‐Acyl‐5‐pyrazolones. European Journal of Inorganic Chemistry, 2014, 7, 1249-1259.
27. Pubblicazione New method for the synthesis of [PtCl {η1-CH2C (O) R}(NN)] ketonyl derivatives starting from the Zeise’s salt. Inorganica Chimica Acta, 2014, 413, 109-114.
28. Pubblicazione 1H NMR spectroscopy and multivariate analysis of monovarietal EVOOs as a tool for modulating Coratina-based blends. Foods, 2014, 3(2), 238-249.
29. Pubblicazione Biotechnological potential of the seaweed Cladophora rupestris (Chlorophyta, Cladophorales) lipidic extract. New biotechnology, 2014, 31(5), 436-444.
30. Pubblicazione Viticultural practice and winemaking effects on metabolic profile of Negroamaro. Food Chemistry, 2014, 161, 112-119.
31. Pubblicazione Following the olive oil production chain: 1D and 2D NMR study of olive paste, pomace, and oil. European journal of lipid science and technology, 2014, 116(11), 1513-1521.
32. Pubblicazione Different apoptotic effects of[Pt(O,O′-acac)(γ-acac)(DMS)]and cisplatin on normal and cancerous human epithelial breast cells in primary culture. British Journal of Pharmacology, 2014, 171 5139–5153.
33. Pubblicazione [Pt (O, O’-acac)(γ-acac)(DMS)] Alters SH-SY5Y Cell Migration and Invasion by the Inhibition of Na+/H+ Exchanger Isoform 1 Occurring through a PKC-ε/ERK/mTOR Pathway. PloS one, 2014, 9(11), e112186.
34. Pubblicazione Extraction and characterization of bio-effectors from agro-food processing by-products as plant growth promoters. Chemical and Biological Technologies in Agriculture, 2014, 1(1), 1-17.
35. Pubblicazione Antitumor activity of [Pt(O,O’-acac)(γ-acac)(DMS)] in mouse xenograft model of breast cancer. Cell Death & Disease, 2015, 5(1), e1014.
36. Pubblicazione Novel Platinum (II) compounds modulate insulin-degrading enzyme activity and induce cell death in neuroblastoma cells. Journal of Biological Inorganic Chemistry, 2015, 20(1), 101-108.
37. Pubblicazione Cerebellum neurotransmission during postnatal development:[Pt (O, O′-acac)(γ-acac)(DMS)] vs cisplatin and neurotoxicity. International Journal of Developmental Neuroscience, 2015, 40, 24-34.
38. Pubblicazione Renal Fibrogenesis and Platinum Compounds in a Rat Model: A Novel Pt (II) Complex vs. Cisplatin. Anticancer Research, 2015, 35, 739-752.
39. Pubblicazione 1H NMR metabolic profiling of apulian EVOOs: fine pedoclimatic influences in salento cultivars. Magnetic Resonance in Food Science, 2015, 154-160.
40. Pubblicazione 1H NMR Spectroscopy and MVA Analysis of Diplodus sargus Eating the Exotic Pest Caulerpa cylindracea. Marine Drugs, 2015, 13(6), 3550-3566.
41. Pubblicazione Performance Assessment in Fingerprinting and Multi Component Quantitative NMR Analyses. Analytical Chemistry, 2015, 87(13), 6709–6717.
42. Pubblicazione Neurotoxic Effects of Platinum Compounds: Studies in vivo on Intracellular Calcium Homeostasis in the Immature Central Nervous System. Toxics, 2015, 3(2), 224-248.
43. Pubblicazione Effect of cisplatin on proteasome activity. Journal of Inorganic Biochemistry, 2015, 153, 253-258.
44. Pubblicazione Synthesis of biocompatible polymeric nano-capsules based on calcium carbonate: A potential cisplatin delivery system. Journal of Inorganic Biochemistry, 2015, 153, 284-292.
45. Pubblicazione Comparative analysis of the proximate and elemental composition of the blue crab Callinectes sapidus, the warty crab Eriphia verrucosa, and the edible crab Cancer pagurus. Heliyon, 2016, 2(2), e00075.
46. Pubblicazione Protected Designation of Origin Extra Virgin Olive Oils Assessment by Nuclear Magnetic Resonance and Multivariate Statistical Analysis: “Terra di Bari”, an Apulian (Southeast Italy) Case Study. JAOCS, 2016, 93(3), 373-381.
47. Pubblicazione 1H NMR metabolomic profiling of the blue crab (Callinectes sapidus) from the Adriatic Sea (SE Italy): A comparison with warty crab (Eriphia verrucosa), and edible crab (Cancer pagurus). Food Chemistry, 2016, 196, 601-609.
48. Pubblicazione [Pt(O,O′-acac)(γ-acac)(DMS)] versus cisplatin: apoptotic effects in B50 neuroblastoma cells. Histochemistry and Cell Biology, 2016, 145(5), 587–601.
49. Pubblicazione Robustness of NMR-based metabolomics to generate comparable data sets for olive oil cultivar classification. An inter-laboratory study on Apulian olive oils. Food Chemistry, 2016, 199, 675-683.
50. Pubblicazione Combined effect of surface nano-topography and delivery of therapeutics on the adhesion of tumor cells on porous silicon substrates. Microelectronic Engineering, 2016, 158, 6-10.
51. Pubblicazione Antitumour and antiangiogenic activities of[Pt(O ,O ′-acac)(γ-acac)(DMS)] in a xenograftmodel of human renal cell carcinoma. British Journal of Pharmacology, 2016, 173, 2633–2644.
52. Pubblicazione In Vitro and In Vivo Antitumor Activity of [Pt (O, O′-acac)(γ-acac)(DMS)] in Malignant Pleural Mesothelioma. PloS one, 2016, 11(11), e0165154.
53. Pubblicazione The Potential Exploitation of the Mediterranean Invasive Alga Caulerpa cylindracea: Can the Invasion Be Transformed into a Gain?. Marine Drugs, 2016, 14(11), 210
54. Pubblicazione Metabolic profile comparison of fruit juice from certified sweet cherry trees (Prunus avium L.) of Ferrovia and Giorgia cultivars: A preliminary study. Food Research International, 2016, 90, 281-287.
55. Pubblicazione Harvest year effects on Apulian EVOOs evaluated by 1H NMR based metabolomics. PeerJ, 2016 4, e2740.
56. Pubblicazione Nanostructured polysaccharidic microcapsules for intracellular release of cisplatin. International Journal of Biological Macromolecules, 2017, 99, 187-195.
57. Pubblicazione ESI–MS studies of the reactions of novel platinum(II) complexes containing O,O′-chelated acetylacetonate and sulfur ligands with selected model proteins. BioMetals, 2017, 30(4), 609–614.
58. Pubblicazione 1H NMR and MVA metabolomic profiles of urines from piglets fed withboluses contaminated with a mixture of five mycotoxins. Biochemistry and Biophysics Reports, 2017, 11, 9–18.
59. Pubblicazione Apoptosis by [Pt (O,O′-acac)(γ-acac)(DMS)] requires PKC-δ mediated p53 activation in malignant pleural mesothelioma. PloS one, 2017, 12 (7), e0181114.
60. Pubblicazione Biostimulants from food processing by‐products: agronomic, quality and metabolic impacts on organic tomato (Solanum lycopersicum L.). Journal of the Science of Food and Agriculture, 2018, 98(4), 1426-1436.
61. Pubblicazione Response of Cisplatin Resistant Skov-3 Cells to [Pt(O,O’-Acac)(g-Acac)(DMS)] Treatment Revealed by a Metabolomic 1H-NMR Study. Molecules, 2018, 23,2301.
62. Pubblicazione Long-term effects after treatment with platinum compounds, cisplatin and [Pt(O,O′-acac)(γ-acac)(DMS)]: Autophagy activation in rat B50 neuroblastoma cells. Toxicology and Applied Pharmacology, 2019, 364.
63. Pubblicazione First Insight on the Mucus of the Annelid Myxicola infundibulum (Polychaeta, Sabellidae) as a Potential Prospect for Drug Discovery. Marine Drugs, 2019, 17, 396.
64. Pubblicazione [Pt(O,O’-acac)(γ-acac)(DMS)] Induces Autophagy in Caki-1 Renal Cancer Cells. Biomolecules, 2019, 9,92.
65. Pubblicazione [Pt (O, O'-acac)(gamma-acac)(DMS)]: Alternative Strategies to Overcome Cisplatin-Induced Side Effects and Resistence in T98G Glioma Cells. Cellular and Molecular Neurobiology, 2020, doi.org/10.1007/s10571-020-00873-8.

Sintesi e caratterizzazione di complessi metallici, principalmente del Platino. Reattività di analoghi del cisplatino con basi nucleiche e DNA; Ottenimento di farmaci antitumorali efficaci in linee cisplatino resistenti; Ottenimento di farmaci antitumorali con target non genomici; Applicazioni metabolomiche della Risonanza Magnetica Nucleare finalizzate alla caratterizzazione di substrati biologici ed agroalimentari.